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pentobarbital will reduce the extent or result of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers lessens plasma focus of abemaciclib and its metabolites.pentobarbital will minimize the extent or impact of fosamprenavir by influenc… Read More